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The Perfect 2-Week Italy Itinerary: Rome, Florence & Amalfi Coast

The Perfect 2-Week Italy Itinerary: Rome, Florence & Amalfi Coast

If you're dreaming of an unforgettable Italian adventure, this the Perfect 2-Week Italy Itinerary: Rome, Florence & Amalfi Coast will guide you through the country’s most iconic cities and breathtaking landscapes. From the ancient ruins of Rome to the romantic canals of Venice and the coastal beauty of the Amalfi Coast, experience Italy’s best in just 14 days—without feeling rushed.

The Perfect 2-Week Italy Itinerary: Rome, Florence & Amalfi Coast

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Why This 2-Week Italy Itinerary?

Italy is rich in history, art, food, and natural wonders. With 14 days in Italy, you’ll have enough time to explore major highlights while still enjoying leisurely moments. This itinerary is ideal for first-time visitors who want to balance sightseeing with authentic cultural experiences.

Itinerary Overview:

  • Days 1–4: Rome
  • Days 5–7: Florence (with a day trip to Pisa or Tuscany)
  • Days 8–11: Amalfi Coast (with optional Capri)
  • Days 12–14: Optional: Venice or Cinque Terre

Days 1–4: Rome – The Eternal City

Colosseum in Rome featured in the perfect 2-week Italy itinerary Rome Florence Amalfi Coast

Kick off your Italy itinerary in Rome, a city where ancient history and modern life intertwine.

Highlights:

  • Visit the Colosseum, Roman Forum, and Palatine Hill (book a guided tour to skip the lines).
  • Explore Vatican City: St. Peter’s Basilica, Vatican Museums, and the Sistine Chapel.
  • Toss a coin into the Trevi Fountain and admire the Pantheon.
  • Wander the charming neighborhood of Trastevere for authentic Roman cuisine.

Pro Tip: Buy a Roma Pass for free access to transportation and discounts on attractions.

Days 5–7: Florence – Cradle of the Renaissance

Florence Cathedral dome view part of the perfect 2-week Italy itinerary Rome Florence Amalfi Coast

Next, head to Florence, Italy’s artistic gem and the capital of Tuscany.

Highlights:

  • Climb Brunelleschi’s Dome at Florence Cathedral for stunning city views.
  • Marvel at Michelangelo’s David at the Accademia Gallery.
  • Spend an afternoon at the Uffizi Gallery, home to Botticelli’s The Birth of Venus.
  • Take a day trip to Pisa to see the Leaning Tower or visit a winery in the Tuscan countryside.

Pro Tip: Book museum tickets in advance to avoid long queues.

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Days 8–11: Amalfi Coast – Italy’s Coastal Paradise

Positano on Amalfi Coast included in the perfect 2-week Italy itinerary Rome Florence Amalfi Coast

From Florence, make your way south to the breathtaking Amalfi Coast.

Base yourself in: Positano, Amalfi, or Sorrento.

Highlights:

  • Relax on the beaches of Positano and explore its pastel-colored streets.
  • Visit Ravello’s gardens for sweeping coastal views.
  • Take a day trip to Capri and tour the Blue Grotto.
  • Enjoy a scenic drive or ferry ride between towns.

Pro Tip: Travel light—many coastal towns have steep streets and lots of stairs!

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Days 12–14: Optional Extensions – Venice or Cinque Terre

Depending on your travel style, choose between:

Option 1: Venice

  • Wander the winding canals and Piazza San Marco.
  • Tour Doge’s Palace and the Bridge of Sighs.
  • Take a romantic gondola ride at sunset.

Option 2: Cinque Terre

  • Hike between the five colorful villages overlooking the Ligurian Sea.
  • Relax at Monterosso’s beaches and savor fresh seafood.

Pro Tip: Book trains early for these routes to secure the best fares.

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Getting Around Italy

  • Trains: Use high-speed trains (Frecciarossa/Italo) between major cities.
  • Car rental: Great for exploring Tuscany or the Amalfi Coast, but not necessary for cities like Rome or Florence.
  • Ferries: Recommended for coastal travel in the Amalfi region.

Where to Stay

  • Rome: Stay near Campo de’ Fiori or Trastevere for easy access to landmarks.
  • Florence: Choose accommodations in the historic center or Oltrarno for local vibes.
  • Amalfi Coast: Consider Positano for views, or Sorrento for better transport links.
  • Venice: Opt for a hotel in Cannaregio for a quieter stay, close to main attractions.

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Must-Try Foods Along the Way

  • Rome: Carbonara, amatriciana, supplì
  • Florence: Bistecca alla Fiorentina, ribollita
  • Amalfi Coast: Fresh seafood, lemon desserts, limoncello
  • Venice: Cicchetti, risotto al nero di seppia

Final Tips for a 2-Week Italy Itinerary

  • Travel light with a carry-on if possible.
  • Pre-book popular attractions and trains.
  • Allow time to wander and discover hidden gems off the tourist track.

This Perfect 2-Week Italy Itinerary: Rome, Florence & Amalfi Coast blends iconic landmarks with authentic experiences, giving you the best of Rome, Florence, the Amalfi Coast, and beyond. Whether you're sipping wine in Tuscany or watching the sun set over Positano, Italy’s magic awaits you every step of the way.