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Where to Stay in Florence: A Guide to the Best Neighborhoods

Where to Stay in Florence: A Guide to the Best Neighborhoods

With its Renaissance beauty, rich artistic heritage, and irresistible Tuscan charm, Florence is a dream destination for travelers from around the world. As the birthplace of Michelangelo and home to masterpieces by Botticelli, Brunelleschi, and da Vinci, this city is a cultural treasure trove — and deciding where to stay in Florence can elevate your entire experience.

From historic quarters rich with art and architecture to charming districts with local flavor, each neighborhood in Florence offers a unique perspective. Whether you’re visiting for art, romance, shopping, or food, this guide will help you find the perfect place to call home during your stay.

Where to Stay in Florence

Table Of Content

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1. Duomo (Historic Center) – Best for First-Time Visitors

Where to stay in Florence with views of the best neighborhoods

At the very heart of Florence lies the Duomo neighborhood, named after the iconic Cathedral of Santa Maria del Fiore. This area is within walking distance of the city’s most famous attractions, including the Uffizi Gallery, Ponte Vecchio, and Piazza della Signoria.

Why stay here: Unmatched access to Florence’s top sights, stunning architecture, and bustling piazzas.
Ideal for: First-time visitors, art and history lovers, and those who want to be in the center of it all.

Pro tip: Book well in advance, as this area is always in high demand.

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2. Oltrarno – Best for Local Charm and Artisan Culture

Guide to the best neighborhoods in Florence for your stay

Across the Arno River from the historic center, Oltrarno (literally "beyond the Arno") is a quieter, more authentic slice of Florence. It’s known for its artisan workshops, antique stores, and trendy cafés. Key sights include Palazzo Pitti, the Boboli Gardens, and panoramic views from Piazzale Michelangelo.

Why stay here: A local, bohemian atmosphere with fewer tourists and exceptional food.
Ideal for: Culture seekers, creatives, and those looking for a more relaxed, residential experience.

3. Santa Croce – Best for History and Vibrant Nightlife

Best neighborhoods to stay in Florence travel guide

Home to the majestic Basilica of Santa Croce (resting place of Michelangelo, Galileo, and Machiavelli), this neighborhood blends deep historical roots with a lively modern spirit. The area is known for its excellent restaurants, artisan shops, and dynamic nightlife.

Why stay here: Rich cultural history mixed with a youthful, energetic vibe.
Ideal for: History lovers, night owls, and those wanting to explore on foot.

Don’t miss: The vibrant leather market and local trattorias tucked into quiet side streets.

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4. San Lorenzo & San Marco – Best for Markets and Museums

Just north of the Duomo, the San Lorenzo area is a bustling hub of markets, museums, and local flavor. Here, you'll find the Mercato Centrale, Florence’s historic food hall, as well as the Medici Chapels and Accademia Gallery, home of Michelangelo’s David.

Why stay here: Central yet less touristy, with easy access to key attractions and authentic Florentine experiences.
Ideal for: Budget travelers, foodies, and those wanting to mix sightseeing with local living.

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5. Santa Maria Novella – Best for Transport and Convenience

Located around the city’s main train station, Santa Maria Novella is ideal for those traveling by rail or planning day trips to other Tuscan cities. The neighborhood has undergone revitalization in recent years and now features boutique hotels, stylish restaurants, and the beautiful Santa Maria Novella church.

Why stay here: Excellent transport links, affordable accommodations, and easy access to the rest of Tuscany.
Ideal for: Business travelers, regional explorers, and practical-minded visitors.

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6. Santo Spirito – Best for a Bohemian Vibe and Artisan Culture

Nestled within the Oltrarno district, Santo Spirito is Florence’s hip, artsy enclave. With its lively piazza, vintage shops, local boutiques, and vibrant aperitivo scene, this neighborhood offers a more off-the-beaten-path take on the city.

Why stay here: A creative, youthful energy paired with authentic Florentine character.
Ideal for: Young travelers, artists, and those seeking a trendy yet traditional vibe.

Must-do: Enjoy a drink on the steps of Piazza Santo Spirito and mingle with locals at sunset.

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7. Campo di Marte – Best for Longer Stays and Local Life

A residential district just outside the historic center, Campo di Marte offers a quieter stay while still being easily accessible by public transportation. It’s a great area for longer visits, with more spacious accommodations and a local feel.

Why stay here: Peaceful, family-friendly, and away from the tourist crowds.
Ideal for: Long-term travelers, families, and those seeking a more authentic daily routine.